Relieving exertional dyspnea during the 3-min constant speed shuttle test in patients with COPD with indacaterol/glycopyrronium <i>versus</i> tiotropium: the RED trial.

Compared with tiotropium alone, indacaterol/glycopyrronium led to additional improvement in IC (80–110 ml), and reduction in FRC (90–160 ml) and residual volume (RV) (130–220 ml), although these differences did not reach statistical significance at all time points.

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