Treatment with daptomycin alone against tissue cages colonized with 1457 icaADBC::dhfr resulted in a mean 1.66 × 10 3 cfu/mL per tissue cage; however, this result did not reach statistical significance ( P = 0.06) (Figure 6 ).
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Rifampicin enhances activity of daptomycin and vancomycin against both a polysaccharide intercellular adhesin (PIA)-dependent and -independent Staphylococcus epidermidis biofilm.
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