Argonaute binding within 3'-untranslated regions poorly predicts gene repression.

Nucleic Acids Res · 2020 · PMC7367155 · PMID 32501500

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highly significantno p-value reported

Genes were chosen based on the presence of at least one highly significant cluster of RNAseq reads within the 3′-UTR (Figure 7A , Supplemental Figure S5A-C).

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a strong trendno p-value reported

While the magnitude of changes for AGO1 and AGO2 knockout cells are less, there is a strong trend among all knockout AGO knockout cell lines separating down-regulated and up-regulated genes.

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