Colonoscopy is safe and not associated with higher pain scores in patients with hypermobility spectrum disorder: results from an exploratory prospective study.

When corrected for age and gender in a logis-tic regression model, this failed to reach the predefined statistical significance level, although a positive trend remained (OR adj 3.62, 95% CI 1.35–9.72, p = 0.01).

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Both the high prevalence of functional GI disorders (in particular FD) and female predominance in patients with HSD were corroborated in the current study, albeit the higher prevalence of IBS failed to reach statistical significance.

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