Selective Antagonism of A1 Adenosinergic Receptors Strengthens the Neuromodulation of the Sensorimotor Network During Epidural Spinal Stimulation.

In the presence of DPCPX (5 μM), the average time-course of peak amplitudes showed a trend of higher responses compared to control during the first 300 pulses from the beginning of stimulation ( Figures 3B,C mean amplitude = 0.24 ± 0.04 mV in control vs. 0.33 ± 0.12 mV; P = 0.006, paired t -test, t = −5.240; n = 5).

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