One large prospective cohort study showed neonatal death before discharge was not significantly reduced at or beyond 31 weeks, and survival without morbidity did not reach statistical significance after 28 weeks. 15 Additionally, antenatal corticosteroid administration raises concerns about worsening pulmonary status and viral shedding as seen in other respiratory illnesses, thus the Society for Maternal-Fetal Medicine (SMFM) currently recommends its use for patients at risk for preterm birth with an upper limit of 34 weeks gestation. 10 Late pre-term steroids after 34 weeks are not recommended.
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