Population Pharmacokinetics and Exposure-Response of Luspatercept, an Erythroid Maturation Agent, in Anemic Patients With Myelodysplastic Syndromes.

CPT Pharmacometrics Syst Pharmacol · 2020 · PMC7376288 · PMID 32602651

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highly significantno p-value reported

Furthermore, the effect of CL/F remained highly significant after accounting for the effects of serum exposure and/or baseline risk factors, including age ( Table 3 ).

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did not reach statistical significanceno p-value reported

The effect of antidrug antibodies on CL/F did not reach statistical significance in the covariate analysis.

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