Antimicrobial Stewardship Programs in Long-Term Care Settings: A Meta-Analysis and Systematic Review.

The subgroup analyses by study design showed that the reduction was similar regardless of study design (interaction P = .37) and remained statistically significant for cluster RCTs (10% reduction; 95% CI = −5% to −14%; P < .001) and uncontrolled pre and post studies (18% reduction; 95% CI = −6% to −29%; P = .006); controlled pre and post studies followed the trend but did not reach statistical significance (15% reduction; 95% CI = −29% to 2%; P = .07).

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