Discussion The final OS analysis showed that OS was numerically longer in the palbociclib plus letrozole arm compared with the letrozole arm, although the results did not reach statistical significance.
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Overall survival results from the randomized phase 2 study of palbociclib in combination with letrozole versus letrozole alone for first-line treatment of ER+/HER2- advanced breast cancer (PALOMA-1, TRIO-18).
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