A novel non-bile acid FXR agonist EDP-305 potently suppresses liver injury and fibrosis without worsening of ductular reaction.

Liver Int · 2020 · PMC7384094 · PMID 32329946

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Serum bilirubin showed a trend towards lower average values in 30mg/kg EDP‐305, but these changes were not statistically significant in multivariate analysis (Figure 4B ).

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