Combination of RERG and ZNF671 methylation rates in circulating cell-free DNA: A novel biomarker for screening of nasopharyngeal carcinoma.

ZNF671 , ITGA4 , and SHISA3 showed a trend of higher methylation rates in ccfDNA samples from NPC patient plasma, although they offered no statistically significant difference between NPC and NNE groups ( P = .059, .101, and .393, respectively). 3.4 Methylation rates in ccfDNA can serve as NPC screening marker Individual methylation rates of candidate genes in ccfDNA samples from NPC and NNE patients are shown in Figure 4 (left).

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