SIRT3 is a downstream target of PPAR-α implicated in high glucose-induced cardiomyocyte injury in AC16 cells.

Exp Ther Med · 2020 · PMC7388318 · PMID 32742361

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showed a trendno p-value reported

Moreover, the protein levels of cleaved caspase-3, Bax and p-JNK1/2 displayed trends consistent with apoptosis, whereas Bcl2 protein level showed a trend opposite to Bax.

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