CFTR Modulators Dampen <i>Aspergillus</i>-Induced Reactive Oxygen Species Production by Cystic Fibrosis Phagocytes.

A decrease in ROS production by CF PMN was observed following pre-treatment with ivacaftor (11,361; −33.4 ± 25.9%, 15,115; −24.1 ± 27.5%) and lumacaftor (11,361; −48.9 ± 11.01%, 15,115; −45.3 ± 9.5%) when compared to untreated controls, although the changes did not reach statistical significance.

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