In contrast to our previous observation that the preceding internalization of allogeneic apoptotic neutrophils upregulates the LPS + IFN‐γ‐induced secretion of the pro‐inflammatory cytokines, in the autologous assay system the production of IL‐8, IL‐6, TNF‐α and IL‐12 by autologous apoptotic cell‐primed moDCs showed a trend to be lower than that by nonprimed moDCs (Fig. 2 ).
← all excerpts
Autologous apoptotic neutrophils inhibit inflammatory cytokine secretion by human dendritic cells, but enhance Th1 responses.
1
—
—