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Distinct fibroblast functional states drive clinical outcomes in ovarian cancer and are regulated by TCF21.

J Exp Med · 2020 · PMC7398174 · PMID 32434219

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Of 10 mice implanted in each group, take rates were 6/10, 5/10, 6/10, and 9/10 for the no CAF control, 363FL CAFs, 374FL CAFs, and 851FH CAFs, respectively, suggesting a possible enhancement of take rate in spheroids containing FAP-high CAFs, although differences did not reach statistical significance.

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