<i>TERT</i> Promoter Mutation C228T Increases Risk for Tumor Recurrence and Death in Head and Neck Cancer Patients.

Front Oncol · 2020 · PMC7399085 · PMID 32850388

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0680

boldest claim

The sentences

marginally significantp = 0.051so close (0.05 < p ≤ 0.1)

In the multivariable Cox regression model including T-stage, N-stage, clinical stage, surgical margins, and the status of C228T for overall survival, clinical stage remained significant (HR = 2.373; 95% CI: 1.072–5.256; p = 0.033) and the status of C228T was marginally significant (HR = 2.352; 95% CI: 0.995–5.558; p = 0.051).

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showed a trendp = 0.068so close (0.05 < p ≤ 0.1)

Our data showed a trend in significance with 91.7% of all mutations occurring in the oral cavity ( p = 0.068), which was similar to the results reported by Barczak et al.

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