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Comparison of Two Dietary Supplements for Treatment of Uric Acid Renal Lithiasis: Citrate vs. Citrate + Theobromine.

Nutrients · 2020 · PMC7400936 · PMID 32645831

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Although the efficacy of citrate + theobromine treatment was better, this did not reach statistical significance, possibly because the citrate dose alone was very effective in the present case and there was no excessive increase in pH probably because of the low dose that was administered.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.