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The presence of tumour-infiltrating lymphocytes (TILs) and the ratios between different subsets serve as prognostic factors in advanced hypopharyngeal squamous cell carcinoma.

BMC Cancer · 2020 · PMC7406390 · PMID 32758195

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One study even found a negative effect of CD8+ TILs on survival, but this did not reach statistical significance in multivariate analysis [ 28 – 30 ].

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