Treatment of Coronavirus Disease 2019 Patients with Convalescent Plasma Reveals a Signal of Significantly Decreased Mortality.

Multivariate analysis, in a model excluding variables that were used in the propensity score match, showed that the risk of mortality within 28 days was increased in patients who were not transfused with convalescent plasma (regardless of titer or timing), with a trend toward significance (adjusted hazard ratio, 2.73; 95% CI, 1–7.48; P = 0.051) ( Supplemental Tables S5 and S6 ).

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Outcomes A decreased probability of death within 28 days post-day 0 was observed in the transfused cohort relative to propensity score–matched controls, although the difference did not reach statistical significance ( Figure 2 A).

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