Increases in cholecystectomy for gallstone related disease in South Africa.

Sci Rep · 2020 · PMC7419551 · PMID 32782347

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a significant trendno p-value reported

In period 2 of the study there was a significant trend for younger patients to have a cholecystectomy.

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an increasing trendno p-value reported

It was noted, however, that there was an increasing trend of patients with gallstone disease and the number of cholecystectomies being performed 5 , 6 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.