Differential myocardial fibrosis of the systemic right ventricle and subpulmonary left ventricle after atrial switch operation for complete transposition of the great arteries.

There is a significant trend on progressive increase in ECV value from the basal towards the apical segments in both the right (p = 0.002) and the left (p < 0.001) ventricle.

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4 Discussion The important observations of the present CMR T1 mapping study conducted in the largest cohort of adult TGA patients after atrial switch operation reported to date include 1) evidence of myocardial fibrosis, as reflected by the greater native T1 and ECV values, involving both the systemic right ventricle and subpulmonary left ventricle, 2) greater segmental and average ECV of the left ventricle compared with that of the right ventricle, 3) regional differences of myocardial fibrosis with an increasing trend of ECV from base to apex of both ventricles, and 4) significant positive correlations between RV and LV native T1 and ECV values.

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