Associations of sleep quality, sleep apnea and autonomic function with insulin secretion and sensitivity: HSCAA study.

When subjects with diabetes type (n = 56) were excluded from analyses, similar trends of associations of PSQ with insulinogenic index were observed with borderline significance (Model 1: p = 0.086, Model 4: p = 0.11, Model 5: p = 0.057, Model 7: 9 = 0.074) probably due to decrease in statistical power. 4 Discussion Sleep has been shown to be associated with development of type 2 diabetes mellitus in population studies [ 14 , 15 ], though there are various factors related to sleep problems, including sleep duration, sleep efficiency, sleep quality, diurnal rhythm, sleep disordered breathing, and autonomic nervous dysfunction.

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Even though activity index showed only a weakly significant association with AHI and not with SDNN in the present cohort ( Supplemental Fig.

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