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Opinion on the re-evaluation of starch sodium octenyl succinate (E 1450) as a food additive in foods for infants below 16 weeks of age and the follow-up of its re-evaluation as a food additive for uses in foods for all population groups.

EFSA J · 2020 · PMC7425341 · PMID 32817762

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showed a trendno p-value reported
Relative organ weight data showed a trend for increased liver and kidney weight with increased concentration of the substituted starch in the diet.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.