Tacrolimus Improves the Implantation Rate in Patients with Elevated Th1/2 Helper Cell Ratio and Repeated Implantation Failure (RIF).

However, the differences did not reach statistical significance. mRNA and protein expression of endometrial markers in endometrial samples The expression of IL-4, IL-10, IL-17, IFN-γ, LIF, and p53 mRNA in the endometrial samples was not statistically different with and without tacrolimus treatment ( Fig. 2 a ).

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