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Comparison of open and closed hyperthermic intraperitoneal chemotherapy: Results from the United States hyperthermic intraperitoneal chemotherapy collaborative.

World J Gastrointest Oncol · 2020 · PMC7428797 · PMID 32864043

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They did not find any differences in morbidity or mortality, and though patients who underwent closed HIPEC tended toward more stable hemodynamics than those undergoing open HIPEC, this did not reach statistical significance[ 9 ].

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