Impact of Cross-Coupling Reactions in Drug Discovery and Development.

Molecules · 2020 · PMC7436090 · PMID 32751973

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a strong trendno p-value reported

In addition of new methodology to remove traces of palladium or other catalysts, there is a strong trend to develop more “green” or environmentally friendly approaches to minimize potential toxicity to the ecosystem.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.