Secondary sclerosing cholangitis in critically ill patients has a poor outcome but lower tumour incidence than primary sclerosing cholangitis.

In multivariate Cox regression analysis low levels of C-reactive protein (hazard ratio 4.687 (95% confidence interval (CI) 1.144–19.199, p = 0.032) were significantly associated with a prolonged survival whereas higher age (hazard ratio 0.488 (95% CI 0.23–1.038), p = 0.062) showed a trend for shorter survival in SSC-CIP.

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Multivariate Cox regression analysis revealed that low levels of CRP (<8 mg/L, hazard ratio 4.687 (95% CI 1.144–19.199, p= 0.032) were significantly associated with a prolonged transplant-free survival whereas higher age (≥35 years, hazard ratio 0.488 (95% CI 0.23–1.038), p = 0.062) showed a statistical trend for shorter transplant-free survival in patients with SSC-CIP ( Table 3 ).

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