RACK7 recognizes H3.3G34R mutation to suppress expression of MHC class II complex components and their delivery pathway in pediatric glioblastoma.

Sci Adv · 2020 · PMC7439511 · PMID 32832624

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0.1900

closest p · 3.8× alpha

0.1900

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The sentences

did not reach statistical significanceP = 0.19not close (p > 0.1)

In a more refined cohort ( n = 99) trying to match location of H3.3G34R/V HGGs, the trend to lower expression in H3.3G34R/V tumors ( n = 19), compared with cortical pediatric HGGs with wild-type H3 ( n = 80), did not reach statistical significance ( P = 0.19, t test).

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