A comprehensive analysis of RHOA mutation positive and negative angioimmunoblastic T-cell lymphomas by targeted deep sequencing, expression profiling and single cell digital image analysis.

RHOA G17V mutated cases have better overall survival than RHOA mutation negative cases Although treatments were different in our study group ( Table I ), the results from overall survival and relapse-free survival demonstrated that the RHOA mutation negative cases had a shorter relapse-free survival and showed a trend towards shorter overall survival ( Fig. 5 ).

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