The influence of aging and duration of nerve injury on the antiallodynic efficacy of analgesics in laboratory mice.

Pain Rep · 2020 · PMC7447376 · PMID 32903926

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0800

boldest claim

The sentences

highly significantP < 0.001actually significant

Spared nerve injury allodynia and sex differences An ANOVA performed on % allodynia data unexpectedly revealed a highly significant interaction between condition and sex (F 2,123 = 23.0, P < 0.001).

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difference was apparentP = 0.08so close (0.05 < p ≤ 0.1)

It is rather difficult to characterize this as an effect of “aging,” since the difference was apparent at 18 weeks of age (compared with 8 weeks of age in the Young-Young and Young-Old conditions), and did not become statistically greater ( P = 0.08) when Old-Old mice were retested at 12 months of age.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.