In monocytes primed with LPS for 6 h and stimulated with ATP for 30 min, there was a dose-dependent trend for BaSO 4 nanoparticles to inhibit IL-1β release, which did not reach statistical significance (Supplementary Fig. 2g ).
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Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis.
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