Is background methotrexate advantageous in extending TNF inhibitor drug survival in elderly patients with rheumatoid arthritis? An analysis of the British Society for Rheumatology Biologics Register.

Rheumatology (Oxford) · 2020 · PMC7449803 · PMID 31998962

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did not reach statistical significanceno p-value reported

We did however confirm the association with leflunomide and lower TNFi treatment survival, which has also been demonstrated in the German registry, although this did not reach statistical significance [ 38 ].

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