Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis.

Redox Biol · 2020 · PMC7452134 · PMID 32810738

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showed a trendno p-value reported

Only with a knockdown of either FTMT or both ferritins RSL-3 was able to reduce cell viability under normoxia, while the siRNA approach to lower FTH showed a trend similar to FTMT but did not reach significance.

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