Lipid mediators and biomarkers associated with type 1 diabetes development.

These assessments identified increases in PGE 2 , PGD 2 , PGA 2 , 15-HETE, and LTE 4 , and a decrease in precursor LTC 4 , in the Aab ++ group that were significant ( P < 0.05) or approached significance ( Figure 7, A–F ), as reflected by Pearson, Kendall, and Spearman rank order correlation analyses ( Table 1 ).

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