Chest roentgenography is complementary to interferon-gamma release assay in latent tuberculosis infection screening of rheumatic patients.

In Taiwan, TNF inhibitor (TNFi) was reimbursed by National Health Insurance since 2003, and LTBI screening and prophylaxis policy of rheumatic patients with biologic therapy was announced by Taiwan Food and Drug Administration in 2012, after which the incidence of tuberculosis tended to decrease but did not reach statistical significance [ 20 ].

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