Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver.

In contrast to the male mice, the alterations in protein expression in regard to Hh signalling in the female SAC-KO mice were not predicted to lead to a clear trend of up- or downregulation for complexes I-IV ( Figure 1 B).

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