nearly significantP = 0.06
Results from three previous meta-analyses are varied, with one reporting significant reduction in pain with MPFF or flavonoid (RR 0.35, 95% CI 0.18–0.69) treatment [ 8 ], one a nearly significant benefit ( P = 0.06) [ 13 ], and one no significant benefit ( P = 0.47) [ 41 ].