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Long-term trends in the prescription of antidiabetic drugs: real-world evidence from the Diabetes Registry Tyrol 2012-2018.

BMJ Open Diabetes Res Care · 2020 · PMC7467522 · PMID 32873600

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showed a trendno p-value reported
32 33 The latest ADA, EASD and ESC guidelines showed a trend toward novel antidiabetic drugs in initial treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.