Given that both individual studies found a significant increase in mortality after SC in large samples [229,274 ( 17 ) and 13,776 ( 59 )], it is likely our trend toward significance would become significant upon inclusion of future studies.
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Shedding Light on "the Hole": A Systematic Review and Meta-Analysis on Adverse Psychological Effects and Mortality Following Solitary Confinement in Correctional Settings.
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In addition, meta-analysis of two mortality studies (n = 243,050) showed a trend for a moderate effect for mortality by any or unnatural causes (i.e., suicide, homicide, overdose, and accidents).