Sleep fragmentation increases blood pressure and is associated with alterations in the gut microbiome and fecal metabolome in rats.

Although group differences in the grouped succinate-producing bacteria and fecal succinate levels did not reach statistical significance between SF and control rats, the association between relative abundance levels of putative succinate-producing taxa and MAP was the strongest of any group observed (Supplemental Table S6; https://doi.org/10.6084/m9.figshare.12149328 ), and this was supported by metabolite analysis of succinate.

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