COX-2/PGE<sub>2</sub> axis regulates hippocampal BDNF/TrkB signaling via EP2 receptor after prolonged seizures.

Epilepsia Open · 2020 · PMC7469770 · PMID 32913950

Europe PMC DOI

hedged sentences

0.0710

closest p · 1.4× alpha

0.0710

boldest claim

The sentences

an evident trendP = .071so close (0.05 < p ≤ 0.1)

24 In line with the findings in pilocarpine models, a one‐hour episode of SE by kainic acid showed an evident trend of increase in hippocampal COX‐2 mRNA levels at 3 days after SE ( P = .071, Figure 4A ) and was able to double the BDNF mRNA expression in the hippocampus ( P < .05, Figure 4B ).

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showed a trendno p-value reported

29 In line with these previous findings, we found that the TG6‐10‐1‐treated mice only showed a trend of decrease in hippocampal BDNF mRNA expression at 1 day after SE when compared to their vehicle‐treated peers.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.