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Serum IL-1RA levels increase from follicular to luteal phase of the ovarian cycle: A pilot study on human female immune responses.

PLoS One · 2020 · PMC7470260 · PMID 32881904

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Human urine samples taken over the course of the menstrual cycle show lowest levels of IL-1RA during menses; and experiments with LPS-stimulated monocytes show increased secretion of IL-1β following ovulation, along with an upward trend of IL-1RA that did not reach statistical significance [ 40 , 41 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.