Compared to the negative control, pre-miR-200c strongly diminished the expression of Ace2 as shown in qRT-PCR and western blot while the other two candidates showed a weaker downregulation that did not reach statistical significance ( Fig. 2 A&B, Supplementary Fig. 1 B).
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MicroRNAs targeting the SARS-CoV-2 entry receptor ACE2 in cardiomyocytes.
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