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Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19.

Pharmacol Ther · 2020 · PMC7476892 · PMID 32910933

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an increasing trendno p-value reported
Besides, there is an increasing trend of CQ-resistance in P. vivax in recent years .

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showed a trendno p-value reported
Moreover, while the zidovudine group showed a trend of drug resistance after 8 weeks of treatment, no patient in the HCQ group showed increased HIV-1 RNA levels or cultured virus throughout the trial.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.