Besides, there is an increasing trend of CQ-resistance in P. vivax in recent years .
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Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19.
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The sentences
Moreover, while the zidovudine group showed a trend of drug resistance after 8 weeks of treatment, no patient in the HCQ group showed increased HIV-1 RNA levels or cultured virus throughout the trial.