Impairments in sensory-motor gating and information processing in a mouse model of <i>Ehmt1</i> haploinsufficiency.

On the EPM ( Figure 2(a) and ( b )), Ehmt1 D6Cre/+ mice spent on average twice as long as Ehmt1 Fl/+ cage-mates on the open-arm (t 26 = −2.08, p = 0.04) and made on average 40% more entries into the open arm of EPM more than controls, although this did not reach statistical significance (t 26 = −1.52, p = 0.14).

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