Interestingly, at a later time point, day 2 post-infection, we observed elevated serum IL-18 in Gsdmd −/− mice, and a trending elevation in Casp1 −/− Casp11 −/− mice that did not reach statistical significance ( Figures 4J and 4K ).
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Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium.
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