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Selection of the Recommended Phase 2 Dose for Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1.

Clin Pharmacol Ther · 2020 · PMC7484916 · PMID 31955412

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showed a trendno p-value reported
14 Univariable logistic regression analyses of the probability of being a responder as a function of exposure (both AUC 0–336 h and C trough,sd ) showed a trend toward a positive association ( Figures 3 a and S2 , Table 1 ), and 95% CIs for the OR overlapped 1.

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