Another miRNA that was expressed higher in ccrcc2_3 tumors and showed a trend towards good prognosis is miR-10b. miR-10b was discriminatory for the good-prognosis miRNA cluster in the TCGA cohort, is part of two prognostic ccRCC signatures and is expressed higher in non-metastatic ccRCC [ 4 , 5 , 9 ].
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MicroRNA expression profiles in molecular subtypes of clear-cell renal cell carcinoma are associated with clinical outcome and repression of specific mRNA targets.
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