IL-6 trans-signaling induces plasminogen activator inhibitor-1 from vascular endothelial cells in cytokine release syndrome.

Proc Natl Acad Sci U S A · 2020 · PMC7486751 · PMID 32826331

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failed to reach statistical significanceno p-value reported

Although the circulating IL-8 concentration trended higher in the seven patients with severe COVID-19 compared with the healthy controls, the difference failed to reach statistical significance ( Fig. 4 A ).

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