Pre-symptomatic Caspase-1 inhibitor delays cognitive decline in a mouse model of Alzheimer disease and aging.

Nat Commun · 2020 · PMC7486940 · PMID 32917871

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did not reach statistical significanceno p-value reported

VX-765 treatment reduced full-length Casp1 levels slightly compared to vehicle-treated J20 mice, but this did not reach statistical significance.

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